Tetrahedron Letters p. 6991 - 6992 (1998)
Update date:2022-08-25
Topics:
Fitt, John
Prasad, Kapa
Repic, Oljan
Blacklock, Thomas J.
A highly useful method for the acylation of amines with acid chlorides utilizing sodium 2-ethylhexanoate as the base is described. This procedure is superior to the Schotten-Baumann conditions whenever the product is water soluble.
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