A practical synthesis of chloroacetylene via phase-transfer catalysis

Article abstract of DOI:10.1055/s-1992-26219

Chloroacetylene (1) was synthesized as solution in hexane from 1,1-dichloroethene (2) in the presence of 50% aqueous sodium hydroxide and tetrabutylammonium hydrogen sulfate as a catalyst (PTC), in moderate yield. Reaction of 2-phenylpropiononitrile with 1 afforded the corresponding 3-butynenitrile 3 in good yield.