New neplanocin analogues. IX. A practical preparation of (6'R)-6'-C- methylneplanocin A (RMNPA), a potent antiviral agent, and the determination of its 6'-configuration. Diastereoselective deamination by adenosine deaminase

DOI: 10.1248/cpb.45.138

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 138 - 142 (1997)

Update date:2022-08-11

Topics:

Authors:

Shuto, Satoshi

Obara, Takumi

Yaginuma, Satoshi

Matsuda, Akira

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.138

We previously synthesized (6'R)- and (6'S)-6'-C-methylneplanocin A's (2a and 2b, respectively), and found that one of them has a potent antiviral activity, though its 6'-configuration has not been confirmed. This report describes the determination of the

Full text of DOI:10.1248/cpb.45.138

NII-Electronic Library Service

Products guided by the article

Product name:(1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-[(1S)-1-hydroxyethyl]cyclopent-3-ene-1,2-diol

Cas No:138662-99-4

R&D Labs maybe for 138662-99-4

Sarchem Laboratories, Inc.

Contact:732.938.2777

Address:5012 Industrial Road Farmingdale, NJ 07727
Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China
X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
Shanghai Mio Chemical Co., Ltd

Contact:0086 21- 64401188-622

Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China

Relevant to this article

Molybdenum nitrogenase catalyzes the reduction and coupling of CO to form hydrocarbons

Doi:10.1074/jbc.M111.229344
(2011)
Saturated Nitrogen-Containing Heterocycles. 17. Synthesis and Catalytic Hydrogenation of 9,10-Substituted Decahydroacridines (Mechanism of Hydroamination of β-Cycloketols)

Doi:10.1007/BF01170743
(1995)
Doi:10.1007/BF01134734
()
Doi:10.1021/jo01352a001
(1957)
Polybromide salts of tetraalkyl and N-heterocyclic cations: New entries into the structural library

Doi:10.1016/j.ica.2017.10.008
(2018)
A Facile and Selective 1,2-Reduction of Conjugated Ketones with NaBH4 in the Presence of CaCl2

Doi:10.1246/cl.1991.1847
(1991)

Article Doi