Solvolytic Stereoselective Coupling of p-Methoxyphenylmagnesium Bromide with Substituted Allylic Chlorides

Article abstract of DOI:10.1016/S0040-4020(01)88206-5

The α- and γ-coupling reactions of a few substituted allylic chlorides with p-methoxyphenylmagnesium bromide were concluded as to involve the formation of an intimate ion-pair intermediate.The solvents used gave substantial effects both on the regio-and stereo-selectivity of the reaction.