Tetrahedron Letters p. 53 - 56 (1985)
Update date:2022-08-11
Topics:
Villieras, Jean
Rambaud, Monique
Graff, Micheline
Heterogenous media of low basicity (K2CO3 or KHCO3), liquid-liquid or solid-liquid allow the Wittig-Horner reaction of fragile and unprotected aldehydes (hydroxyaldehydes, nitroaldehyde and ketoaldehydes) with excellent yields.The reaction is applied to the synthesis of Royal Jelly acid and Queen Substance of Honey bee.
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