A convenient method for chemoselective O-methylation of hydroxypyridines

Article abstract of DOI:10.1080/00397919908086473

ethereal-diazomethane in tert-butanol at -20 °C to rt, afforded the corresponding 3-methoxypyridine derivatives (2a-g) in 54-94% yield.

Full text of DOI:10.1080/00397919908086473

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic Organic
Chemistry
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A Convenient Method for
Chemoselective O-Methylation of
Hydroxypyridines
Maciej Adamczyk a , Donald D. Johnson a & Rajarathnam E.
Reddy a
a Division Organic Chemistry Research (9NM, AP20) ,
Diagnostic Division, Abbott Laboratories , 100 Abbott Park
Road, Abbott Park, IL, 60064-6016
Published online: 25 Sep 2007.
To cite this article: Maciej Adamczyk , Donald D. Johnson & Rajarathnam E. Reddy (1999)
A Convenient Method for Chemoselective O-Methylation of Hydroxypyridines, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic Organic
Chemistry, 29:17, 2985-2993, DOI: 10.1080/00397919908086473
To link to this article: http://dx.doi.org/10.1080/00397919908086473
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