Labelled compounds of potential biological interest. VI. Preparation of some labelled local anesthetic aminoethers

Article abstract of DOI:10.1002/jlcr.2580140502

2'-(2-Diisopropylaminoethoxy)-butyrophenone (ketocaine) and 1-butoxy-2-(2-diisopropylaminoethoxy)-benzene show a good anaesthetic effect on topical application. The synthesis of both of these compounds specifically labelled with ¹⁴C is described. The preparation of ketocaine generally labelled with tritium and specifically labelled with deuterium is also reported.