Journal of the Chinese Chemical Society p. 413 - 416 (1997)
Update date:2022-08-29
Topics:
Chin, Tsung-Mei
Huang, Liang-Kuen
Kan, Lou-Sing
Chlorination of ribofuranose or 2-deoxyribofuranose derivatives was carried out in a 1,4-dioxane solution of hydrogen chloride. This improved procedure allowed the syntheses of 1-chloro-α-D-ribofuranose and 1-chloro-2-deoxy-α-D-ribofuranose derivatives and offered ease of handling, high yield, and the stereo-controlled α-configuration at C-1.
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