First example of high asymmetric induction at the 'pseudo-micellar' interface of a chiral amphiphilic dendrimer

Article abstract of DOI:10.1016/S0040-4039(99)00331-7

Sodium borohydride reduced, at the chiral interface of an amphiphilic dendrimer, prochiral ketones to the corresponding chiral alcohols in high yields (>90%) with enantioselectivities over 95% in THF (ex: ee of 99.4% was obtained in reduction of acetophen