UPDATES
Tiziana Bellavista et al.
CDCl3): d=7.32–7.16 (m, 3H), 7.07 (d, J=7.2 Hz, 2H), 5.77
(m, 1H), 5.17 (dd, J=14.7, 9.6 Hz, 1H), 4.78 (dd, J=14.7,
3.9 Hz, 1H), 3.98 (s, 3H), 3.96 (s, 3H), 2–79–2.40 (m, 3H),
2.30 (m, 1H); 13C NMR (100 MHz, CDCl3): d=160.4, 158.9,
140.0, 139.0, 131.5, 129.0, 128.4, 126.9, 77.1, 57.6, 53.9, 53.1,
34.2, 31.6; FT-IR (KBr): n=3383, 3734, 2427, 1733, 1558,
1456, 1227 cmÀ1; MS (ESI): m/z=363.4 [MH+, 100%], 385.3
[MNa+, 45%], 401.3 [MK+, 22%]. The enantiomeric excess
was determined to be 79% by HPLC (Daicel Chiralpak
AD-H column, 10% 2-propanol/n- hexane, 1 mLminÀ1, UV
220 nm): tminor =33.1 min, tmajor =56.5 min; [a]2D0: +18.2 (c 1.0
in CHCl3).
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Acknowledgements
We thank the University of Salerno (FARB) and the Italian
Ministero dell’Università e della Ricerca (MIUR) for finan-
cial support. A. L. thanks the European Union, COST
Action CM0905-Organocatalysis.
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