Organic Letters p. 2829 - 2831 (2000)
Update date:2022-08-11
Topics:
Kemperman, Gerardus J.
Zhu, Jie
Klunder, Antonius J. H.
Zwanenburg, Binne
The cephalosporin antibiotic Cefadroxil can be epimerized at the α-carbon of its amino acid side chain using pyridoxal as the mediator. By clathration with 2,7-dihydroxynaphthalene, the desired diastereomer can be selectively withdrawn from the equilibrat
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Doi:10.1039/b200462c
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(2000)