Structure-activity relationship studies of CNS agents, Part 23: N-(3-phenylpropyl)- and N-[(E)-cinnamyl]-1,2,3,4-tetrahydroisoquinoline mimic 1-phenylpiperazine at 5-HT1A receptors.

DOI: 10.1002/ardp.19953280707

Source and publish data:

Archiv der Pharmazie p. 604 - 608 (1995)

Update date:2022-08-17

Topics:

Authors:

Mokrosz Mokrosz

Bojarski

Charakchieva-Minol

Duszynska

Mokrosz Mokrosz

Paluchowska

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Article abstract of DOI:10.1002/ardp.19953280707

The 5-HT1A receptor affinities and ionization constants of a set of 1-arylpiperazine (4) 1,2,3,4-tetrahydroisoquinoline (6), and -quinoline (7) containing N-(omega-arylalkyl) or N-(E)-cinnamyl substituents as well as two morpholine derivatives (8a, 8b) we

Full text of DOI:10.1002/ardp.19953280707

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