Polyaza[n]paracyclophanes as synthetic models of Zn containing enzymes. The role of a non coordinated nitrogen atom in the proximity of the metal

Article abstract of DOI:10.1016/S0040-4020(97)00144-0

2,6,9,13-Tetraaza[14]paracyclophane (3, B323) represents a simple model for Zn containing enzymes like HCAII which possess additional reactive groups in the proximity of the metal center. The Zn²⁺.3 complex shows notable catalytic activity for