Remarkable ligand effect on the enantioselectivity of the chiral lanthanum complex-catalyzed asymmetric epoxidation of enones

Article abstract of DOI:10.1016/S0040-4039(98)01569-X

The addition of triphenylphosphine oxide significantly enhanced the degree of asymmetric induction (up to 96% ee) in the chiral La-binol- complex-catalyzed epoxidation of enones using tert-butyl hydroperoxide as the oxidant. The new protocol is highly general and practical.