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Chemical syntheses of novel fluorescent labelled fatty acids, phosphatidylcholines and cholesterol esters

DOI: 10.1515/bchm2.1976.357.1.7

Source and publish data:

Hoppe-Seyler's Zeitschrift fur Physiologische Chemie p. 7 - 19 (1976)

Update date:2022-08-17

Topics:

Authors:

StoffelStoffel

MichaelisMichaelis

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Article abstract of DOI:10.1515/bchm2.1976.357.1.7

The synthesis of a novel class of fluorescent labelled fatty acids of different chain lengths and unsaturation, phospholipids and cholesterol esters has been developed. The following ω anthracene labelled cis unsaturated fatty acids have been synthesized: ω (9 anthryl) 6c octenoic, 7c nonenoic, 10c dodecenoic, 6c,9c undecadienoic, 10c,13c pentadecadienoic acid. They have been introduced into the 2 position of 1 stearoyl and 1 linoleoyl 3 sn glycerophosphocholine and cholesterol. Mass spectroscopy, 1H NMR, IR and fluorescence spectroscopy and different chromatographic procedures have been applied to confirm and characterize their structures. The properties of the different fluorescent labelled phosphatidylcholines in monomolecular films have been determined by the Langmuir technique.

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Full text of DOI:10.1515/bchm2.1976.357.1.7

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Download Date | 6/11/15 7:50  
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Download Date | 6/11/15 7:50  
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Download Date | 6/11/15 7:50  
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