Journal of Medicinal Chemistry p. 117 - 119 (1981)
Update date:2022-08-17
Topics:
Parsia, Maria T. Di
Suarez, Cecilia
Vitolo, Maria J.
Marquez, Victor E.
Beyer, Bernardo
et al.
The synthesis and study of the oral antiallergic activity of a series of monopyrazole derivatives (2-14) considered as analogues of active bispyrazole 1 are described.None of the compounds showed significant inhibition of the rat passive cutaneous anaphylaxis (PCA), with the exception of the already known 5-aminoindazole (2).The activity of this compound is, however, lower than that of compound 1.
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