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Synthesis of some novel tetrahydronaphthalene benzimidazole derivatives

DOI: 10.1515/HC.2001.7.5.455

Source and publish data:

Heterocyclic Communications p. 455 - 460 (2001)

Update date:2022-08-11

Topics:

Authors:

Ates-Alagoz, ZeynepAtes-Alagoz, Zeynep

Buyukbingol, ErdemBuyukbingol, Erdem

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Article abstract of DOI:10.1515/HC.2001.7.5.455

Retinoids, synthetic and natural analogues of all-trans-retinoic acid (RA), exert their biological effects with responsive elements of DNA to promote on cell differentiation and proliferation and behave as potent adipogenic hormones. Herein, we describe the synthesis of a number of novel tetrahydrotetramethylnaphthalene benzimidazole derivatives as retinoids. Analogs were prepared as depicted in Scheme 1 and 2. As is evident from both shemes, a variety of tetrahydrotetramethylnaphthalene benzimidazole derivatives have been synthesized by using an appropiate NaHSO3 addiction product.

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Full text of DOI:10.1515/HC.2001.7.5.455

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Authenticated  
Download Date | 5/25/15 6:21 PM  
Brought to you by | Purdue University Libraries  
Authenticated  
Download Date | 5/25/15 6:21 PM  
Brought to you by | Purdue University Libraries  
Authenticated  
Download Date | 5/25/15 6:21 PM  
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Product name:Methyl 4-chloro-3-nitrobenzoate

Cas No:14719-83-6

14719-83-6

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