Tetrahedron Letters p. 6423 - 6426 (1993)
Update date:2022-08-28
Topics:
Tatsuta, Kuniaki
Miura, Shozo
Gunji, Hiroki
Tamai, Tetsuro
Yoshida, Ryonosuke
Inagaki, Takashi
A Z-isomer of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid, which is the common acyl moiety of clinically useful cephalosporins, has been prepared from the aminoisoxazols through the thiadiazol-acetate in two pathways.
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(1995)