Nitroimidazoles XVII. Nucleophilic Amination or Ring Transformation in Reactions of 1-Aryl-4-nitroimidazoles with 4-Amino-1,2,4-triazole or Hydroxylamine

Article abstract of DOI:10.1016/S0040-4020(01)82383-8

1-Aryl-4-nitroimidazoles under action of 4-amino-1,2,4-triazole in the presence of MeONa in DMSO undergo a vicarious nucleophilic substitution of hydrogen to give 5-amino-1-aryl-4-nitroimidazoles.If reacted with hydroxylamine in the presence of KOH or MeO