Enantioselective conjugate addition of organocuprate using a chiral amidophosphine ligand

Article abstract of DOI:10.1016/S0040-4039(00)60870-5

Based on the concept of a metal differentiating coordination, a new chiral amidophosphine ligand 2 was designed, synthesized, and applied in an enantioselective conjugate addition of lithium dimethylcuprate to chalcone providing the corresponding adduct i