Journal of the American Chemical Society p. 4108 - 4109 (2004)
Update date:2022-08-23
Topics:
Brochu, Michael P.
Brown, Sean P.
MacMillan, David W. C.
The first direct enantioselective catalytic α-chlorination of aldehydes has been accomplished. The use of enamine catalysis has provided a new organocatalytic strategy for the enantioselective chlorination of aldehydes to generate α-chloro aldehydes, an i
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