Synthesis of phosphorylated tripeptides representing poisoned acetylcholinesterase

Article abstract of DOI:10.1016/0040-4039(93)88096-2

Tripeptide sequences bearing dimethyl phosphate, dimethylphosphorothionate, and O,S-dimethylphosphorothiolate groups at the serine residue were synthesized to serve as active sites models of organophosphate-poisoned acetylcholinesterase.