MODELS OF FOLATE COFACTORS - 24. A ROUTE TO OPTICALLY ACTIVE OCTAHYDROINDOLOQUINOLIZINES

DOI: 10.1016/S0040-4020(01)88242-9

Source and publish data:

Tetrahedron p. 6521 - 6528 (1992)

Update date:2022-08-10

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Authors:

Huizenga, Reinald H.

Pandit, Upendra K.

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Article abstract of DOI:10.1016/S0040-4020(01)88242-9

L-(-)-Tryptophane derivatives react with 2-(3,3-dimethyl-3-ethoxycarbonyl-2-oxopropyl)hexahydropyrimidine to form optically active enamino esters.The latter cyclize under basic conditions to give indolylethylpyridinediones, which, upon treatment with acids give the title compounds.

Full text of DOI:10.1016/S0040-4020(01)88242-9

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