Synthesis and application of new (threo)- and (erythro)-amino alcohols based on the octahydro-cyclopenta[b]pyrrole system in the catalytic enantioselective addition of diethylzinc to benzaldehyde

Article abstract of DOI:10.1016/S0957-4166(97)00327-3

Asymmetric catalytic ethylation of benzaldehyde utilizing a series of new, artificial β-amino alcohols based on the octahydro-cyclopenta[b]pyrrole system is presented. A systematic investigation on the inductive correlation of up to four catalyst-internal