Synthetic study of 2-[(6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl)-sulfinyl]-1H-benzimidazole analogs and their biological broperties as novel proton pump inhibitors

DOI: 10.1248/cpb.43.421

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 421 - 431 (1995)

Update date:2022-08-10

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Authors:

Yamada Yamada

Goto Goto

Yamaguchi

Aihara Aihara

Kogi Kogi

Narita Narita

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Article abstract of DOI:10.1248/cpb.43.421

A series of 2-[(cycloalka[b]pyridinyl)sulfinyl]-1H-benzimidazoles (11) was synthesized and tested for antisecretory activity against pentagastrin-induced gastric acid secretion in rats. A novel benzimidazole derivative containing a cyclohepta[b]pyridine m

Full text of DOI:10.1248/cpb.43.421

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