The first total synthesis of (-)-benzomalvin A via intramolecular Aza-Wittig reactions

Article abstract of DOI:10.1246/cl.1997.869

The first total synthesis of (-)-benzomalvin A 1, which possesses quinazolin-4(3H)-one moiety and 1,4-benzodiazepin-5-one moiety, was described. Both of 6- and 7-membered ring skeletons were efficiently constructed by intramolecular aza-Wittig reactions as the key reactions.