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therapeutic response may be more difficult than initially
thought. Consequently, a more dynamic approach may
provide a better change to reach the goal of predicting
drug efficacy. In this article, we described the expression
profiles MCF-7 cells after exposure to three cytostatic
drugs. It is clear that the molecular response of the MCF-7
cells is different after the exposure to each drug. This is
not surprising because each drug has its own mechanism
of action. However, it contains the promise that dynamic
expression profiling might be the way to determine the
genetic determinants for drug efficacy.
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