2(S)-((3,5-bis(trifluoromethyl)benzyl)-oxy)-3(S)-phenyl-4-((3-oxo-2,2,4- triazol-5-yl)methyl)rnorpholine (1): A potent, orally active, morpholine-based human neurokinin-1 receptor antagonist

DOI: 10.1021/jm950654w

Source and publish data:

Journal of Medicinal Chemistry p. 1760 - 1762 (1996)

Update date:2022-08-10

Topics:

Authors:

Hale, Jeffrey J.

Mills, Sander G.

MacCoss, Malcolm

Shah, Shrenik K.

Qi, Hongbo

Mathre, David J.

Cascieri, Margaret A.

Sadowski, Sharon

Strader, Catherine D.

MacIntyre, D. Euan

Metzger, Joseph M.