Synthesis of arylpiperazines via nucleophilic aromatic substitution of (η6-fluoroarene)tricarbonylchromium complexes

DOI: 10.1016/0040-4039(96)01971-5

Source and publish data:

Tetrahedron Letters p. 8487 - 8488 (1996)

Update date:2022-08-29

Topics:

Authors:

Perez, Michel

Potier, Pierre

Halazy, Serge

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Article abstract of DOI:10.1016/0040-4039(96)01971-5

A one-pot, high yield preparation procedure for the synthesis of arylpiperazines using a nucleophilic aromatic substitution of (η⁶-fluoroarene)tricarbonylchromium complexes (including those bearing electron donating groups) is described. A new, easy and fast decomplexation procedure, in DMSO as solvent, is also presented.

Full text of DOI:10.1016/0040-4039(96)01971-5

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