The preparation of immunosuppressant SR-31747

Article abstract of DOI:10.1080/00397919708006827

The preparation of immunosuppressant SR-31747 is described. Attempts to install the Z-allyl amine included Lindlar partial hydrogenation and vinyl stannane methodologies. Ultimately, the Wittig olefination of aidehyde 12 with the ylide derived from β-amin

Full text of DOI:10.1080/00397919708006827

This article was downloaded by: [National Sun Yat-Sen University]
On: 27 December 2014, At: 04:18
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
The Preparation of
Immunosuppressant SR-31747
Laurence E. Burgess a
a Central Research Division , Pfizer Inc. , Groton, CT,
06340
Published online: 22 Aug 2006.
To cite this article: Laurence E. Burgess (1997) The Preparation of
Immunosuppressant SR-31747, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 27:12, 2181-2191, DOI:
10.1080/00397919708006827
To link to this article: http://dx.doi.org/10.1080/00397919708006827
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,
or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and
are not the views of or endorsed by Taylor & Francis. The accuracy of the
Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any
losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or

indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions