ADDITION OF MOLECULAR FLUORINE TO BICYLCOHEPT-2-ENE DERIVATIVES AND CONVERSION TO FLUORINE-CONTAINING CARBOCYCLIC NUCLEOSIDES

Article abstract of DOI:10.1016/S0040-4039(00)77274-1

Addition of molecular fluorine to bicyclo<2.2.1>hept-2-ene derivatives has been found to give exo,exo-difluoro adducts in fair yields.The difluoro adduct (13c) was converted to the fluorine containing carbocyclic adenosine and guanosine analogs.