Enantioconvergent synthesis of (+)-estrone from racemic 4-tert-butoxy-2-cyclopentenone

DOI: 10.1016/0040-4039(96)01688-7

Source and publish data:

Tetrahedron Letters p. 7403 - 7406 (1996)

Update date:2022-08-10

Topics:

Authors:

Sugahara, Tsutomu

Ogasawara, Kunio

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Article abstract of DOI:10.1016/0040-4039(96)01688-7

(+)-Estrone has been synthesized in an enantioconvergent manner from racemic 4-tert-butoxy-2-cyclopentenone via contrasteric Diels-Alder reaction and lipase-mediated kinetic transesterification as the key steps.

Full text of DOI:10.1016/0040-4039(96)01688-7

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Product name:Estrone 3-methyl ether

Cas No:1624-62-0

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