Synthesis and Biological Evaluation of Substituted Flavones as Gastroprotective Agents

DOI: 10.1021/jm00025a011

Source and publish data:

Journal of Medicinal Chemistry p. 4937 - 4943 (1995)

Update date:2022-08-10

Topics:

Authors:

Ares, Jeffrey J.

Outt, Pamela E.

Randall, Jared L.

Murray, Peter D.

Weisshaar, Pamela S.

et al. et al.

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Article abstract of DOI:10.1021/jm00025a011

Flavone (1) was found to protect against ethanol-induced gastric damage in rats; however, it is known that certain compounds in the flavone class, including flavone itself, are inducers of hepatic drug metabolizing enzymes.With the hope identifying gastro

Full text of DOI:10.1021/jm00025a011

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