Synthesis of thiazoles from the reaction of phenyliodonium ylids of cyclic β-dicarbonyl compounds with thioureas

Article abstract of DOI:10.1002/jhet.5570330307

Phenyliodonium ylids of cyclic β-dicarbonyl compounds react with substituted thioureas to form the corresponding thiouronium ylids. The latter, when they have one free amino group, are converted upon heating to fused thiazoles. The reaction can be considered as a modification of the Hantzsch synthesis.