Tetrahedron Letters p. 7591 - 7594 (1998)
Update date:2022-08-29
Topics:
Barco, Achille
Benetti, Simonetta
De Risi, Carmela
Marchetti, Paolo
Pollini, Gian P.
Zanirato, Vinicio
An efficient method for the construction of 2-substituted-piperidin-4- one derivatives on solid support has been developed using polymer-bound 4- benzylsulfonyl-1-triphenylphosphoranylidene-2-butanone as a convenient precursor for substituted divinyl ketones in the heterocyclization reaction with amines. The resin was released in a recyclable sulfinate form.
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