Reinvestigation to the C-7 epimerization of paclitaxel and related taxoids under basic conditions

Article abstract of DOI:10.1080/00397919708003386

Base-promoted C-7 epimerizations of paclitaxel, 10-deacetylbaccatin III were investigated. It has been found that 13α-OH may play an important role in the equilibrium of C-7 epimers of paclitaxel and related taxoids.

Full text of DOI:10.1080/00397919708003386

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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Reinvestigation to the C-7
Epimerization of Paclitaxel and
Related Taxoids Under Basic
Conditions
Wei-Shuo Fang a , Qi-Cheng Fang a & Xiao-Tian Liang
a
a Institute of Materia Medica, Chinese Academy of
Medical Sciences & Peking Union Medical College ,
Beijing, 100050, P. R. China
Published online: 22 Aug 2006.
To cite this article: Wei-Shuo Fang , Qi-Cheng Fang & Xiao-Tian Liang (1997)
Reinvestigation to the C-7 Epimerization of Paclitaxel and Related Taxoids
Under Basic Conditions, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 27:13, 2305-2310, DOI:
10.1080/00397919708003386
To link to this article: http://dx.doi.org/10.1080/00397919708003386
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