Bioorganic and Medicinal Chemistry Letters p. 1705 - 1708 (2017)
Update date:2022-08-11
Topics:
Phillips, Robert S.
Anderson, Andrew D.
Gentry, Harvey G.
Güner, Osman F.
Bowen, J. Phillip
Kynurenine monooxygenase (KMO) is a potential drug target for treatment of neurodegenerative disorders such as Huntington's and Alzheimer's diseases. We have evaluated substituted kynurenines as substrates or inhibitors of KMO from Cytophaga hutchinsonii.
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