Isolation and characterization of seven lyso platelet-activating factors and two lyso phosphatidylcholines from the crude drug 'Suitetsu' (the leech, Hirudo nipponica)

Article abstract of DOI:10.1248/cpb.41.1366

Nine lyso glycerophospholipids were isolated in the pure state from the crude drug 'Suitetsu', which is the dried body of the leech, Hirudo nipponica (Hirudidae). They were identified as 1-O-hexadecyl-(1), 1-O-octadecyl-(2), 1- O-tetradecyl-(3), 1-O-9-cis-hexadecenyl-(4), 1-O-hexadecanoyl-(5), 1-O- pentadecyl-(6), 1-O-15-methylhexadecyl-(7), 1-O-octadecanoyl-(8) and 1-O- heptadecyl-sn-glycero-3-phosphocholine (9). Two of them (5 and 8) are lysophosphatidylcholines and the other seven are lyso platelet-activating factors. One of them has an alkenyl carbon chain.

Full text of DOI:10.1248/cpb.41.1366

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