REDUCTION PAR LE BOROHYDRURE DE SODIUM D'INDANONES CHROME TRICARBONYLE ENDO SUBSTITUEES EN α ET β. POSITION DE L'ETAT DE TRANSITION ET FACTEURS DE REACTIVITE

Article abstract of DOI:10.1016/S0040-4020(01)97634-3

In the indanone Cr(CO)3 series the substitution of the β endo hydrogen atom by alkyl groups has shown an increased reactivity towards NaBH4 reduction attributed to a deconjugation of carbonyl group.While in the endo α-substituted series, a decreased reactivity controlled by an enhancement of the activation enthalpy has been observed.The steric origin of this effect and its influence on the position of the transition state are discussed.