Substitution and stereochemical effects in the reactions of combined aminonitrile-oxazolidines with a Grignard reagent

Article abstract of DOI:10.1016/S0040-4039(99)00980-6

A study of the reaction of phenyl magnesium bromide with various N- (cyanomethyl)oxazolidines showed that product formation (essentially 3- imidazolines and 2-aminomorpholines) is highly sensitive to the substitution pattern and stereochemistry, and appea