Fragmentation of peroxyhemiacetals. Stereoselective synthesis of 1,2-dioxolanes

Article abstract of DOI:10.1016/0040-4039(96)01360-3

A new and efficient approach to the synthesis of 1,2-dioxolanes by β-fragmentation of alkoxy radicals from readily available peroxyhemiacetals, under mild conditions, is described. The radical reaction proceeds in a diastereoselective manner providing a sole 1,2-dioxolane.