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Biosynthesis of Porphyrins and Related Macrocycles. Part 18. Proof by Spectroscopy and Synthesis that Unrearranged Hydroxymethylbilane is the Product from Deaminase and the Substrate for Cosynthetase in the Biosynthesis of Uropophyrinogen-III

DOI: 10.1039/P19820002427

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2427 - 2444 (1982)

Update date:2022-08-11

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Authors:

Battersby, Alan R.Battersby, Alan R.

Fookes, Christopher J. R.Fookes, Christopher J. R.

Gustafson-Potter, Kerstin E.Gustafson-Potter, Kerstin E.

McDonald, EdwardMcDonald, Edward

Matcham, George W. J.Matcham, George W. J.

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Article abstract of DOI:10.1039/P19820002427

When the enzyme deaminase acts alone on porphobilinogen, it releases a tarnsient intermediate into the medium which is unaffected by further treatment with a large excess of deaminase.The intermediate undergoes rapid ring-closure chemically (t1/2 View More

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Product name:3,8,13,18-tetrakis(carboxymethyl)-5,10,15,20,22,24-hexahydro 21H,23H-Porphine-2,7,12,17-tetrapropanoic acid

Cas No:1867-62-5

1867-62-5

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