Total synthesis of (-)-hemiasterlin, a structurally novel tripeptide that exhibits potent cytotoxic activity

DOI: 10.1016/S0040-4039(96)02335-0

Source and publish data:

Tetrahedron Letters p. 317 - 320 (1997)

Update date:2022-08-11

Topics:

Authors:

Andersen, Raymond J.

Coleman, John E.

Piers, Edward

Wallace, Debra J.

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Article abstract of DOI:10.1016/S0040-4039(96)02335-0

The total synthesis of (-)-hemiasterlin (2), a structurally novel, naturally occurring tripeptide that exhibits potent cytotoxic and antimitotic activity against human breast cancer MCF7 cells, is described.

Full text of DOI:10.1016/S0040-4039(96)02335-0

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