Enantiocontrol by intrinsic antiparallel double repulsion on diacetone-Dglucose template. Enantioselective synthesis of alanine and chirally deuterated glycine

Article abstract of DOI:10.1016/S0040-4039(00)93559-7

A divergent and highly enantioselective synthetic methodology not only for both enantiomers of α-amino acids but for both chirally deuterated glycines from a single starting material was developed by making use of stereocontrol with antiparallel double repulsion on the diacetone-D-glucos-3-ulose template.