Resolution of amino acids in a mixture of 2-methyl-2-propanol/water (19:1) catalyzed by alcalase via in situ racemization of one antipode mediated by pyridoxal 5-phosphate

Article abstract of DOI:10.1021/jo00104a007

Procedures for the conversion of a racemic amino acid into the L-enantiomer by the alcalase catalyzed resolution of the amino acid ester in 2-methyl-2-propanol/water (19:1) simultaneously with the pyridoxal 5-phosphate-catalyzed racemization of the unhydrolyzed antipode have been developed.