Bioorganic and Medicinal Chemistry Letters p. 669 - 674 (1997)
Update date:2022-08-11
Topics:
Cundy, Darren J.
Holan, George
Otaegui, Michelle
Simpson, Gregory W.
Derivatives of 3- and 1-(4'-hydroxy-3'-(hydroxymethyl)butyl)-imidazo[4,5-b]pyridine were prepared in several steps from 2-amino-5-chloropyridine. Selected compounds were evaluated against human cytomegalovirus (HCMV), herpes simplex viruses (HSV1/HSV2) and varicella tester virus (VZV). Details of their synthesis and biological activities are presented.
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Doi:10.1021/jo980799l
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