Tetrahedron Letters p. 8867 - 8870 (1997)
Update date:2022-08-16
Topics:
Gozzi, Christel
Lavenot, Laurence
Ilg, Kerstin
Penalva, Vincent
Lemaire, Marc
Direct thiophene arylation using a Heck-type reaction with Pd(OAc)2/NBu4Br as catalytic system is reported. Reactions with 2- and 3-substituted thiophenes have shown that substituent nature and position influence the cross-coupling.
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