Chemical and Pharmaceutical Bulletin p. 1039 - 1041 (1992)
Update date:2022-08-11
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A general procedure has been developed for the preparation of 9-alkylated adenines by the Mitsunobu reaction between 6-chloropurine and several alcohols, followed by the replacement of the chlorine with ammonia. A lesser amount of the 7-alkylpurines was also obtained, irrespective of the alcohol used.
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Doi:10.1039/c9dt02338k
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