Tetrahedron Letters p. 4463 - 4465 (1999)
Update date:2022-08-11
Topics:
Daniels, Dwayne L.
Richert, Clemens
Conjugate addition of Boc-L-Cys-OH to 3-methylcrotonaldehyde, in situ reduction with sodium borohydride, and in situ deprotection with hydrochloric acid, directly followed by chromatography gives L-felinine in 73% yield. Similar syntheses may produce acid building blocks for combinatorial libraries.
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