Bioorganic and Medicinal Chemistry Letters p. 2229 - 2232 (1999)
Update date:2022-08-17
Topics:
Leung, Wai-Yee
Trobridge, Patty A.
Haugland, Rosaria P.
Haugland, Richard P.
Mao, Fei
7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid (AMCA-S, also called Alexa(TM) 350) 2 was synthesized as a new water-soluble blue fluorescent dye for protein labeling. Compared with its nonsulfonated counterpart (AMCA) 1 the new dye gave significantly higher fluorescence quantum yields on proteins.
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