7-amino-4-methyl-6-sulfocoumarin-3-acetic acid: A novel blue fluorescent dye for protein labeling

DOI: 10.1016/S0960-894X(99)00364-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2229 - 2232 (1999)

Update date:2022-08-17

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Authors:

Leung, Wai-Yee

Trobridge, Patty A.

Haugland, Rosaria P.

Haugland, Richard P.

Mao, Fei

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Article abstract of DOI:10.1016/S0960-894X(99)00364-9

7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid (AMCA-S, also called Alexa(TM) 350) 2 was synthesized as a new water-soluble blue fluorescent dye for protein labeling. Compared with its nonsulfonated counterpart (AMCA) 1 the new dye gave significantly higher fluorescence quantum yields on proteins.

Full text of DOI:10.1016/S0960-894X(99)00364-9

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